Mineralocorticoid Receptor Antagonists
About the Procedure
Mineralocorticoid Receptor Antagonists (MRAs) are medications that block the action of aldosterone, a hormone that causes salt and water retention. By reducing fluid overload and preventing harmful heart remodeling, MRAs improve outcomes in heart failure and resistant hypertension. Commonly used MRAs help lower blood pressure, reduce swelling, and decrease hospitalizations and mortality in selected heart failure patients. Careful monitoring is essential to avoid side effects such as high potassium levels or kidney dysfunction.
Eligibility
- Patients with heart failure with reduced ejection fraction.
- Individuals with resistant or difficult-to-control hypertension.
- Patients with post–heart attack heart failure symptoms.
- Selected patients with fluid retention despite standard therapy.
Care Before Medication
- Review kidney function and baseline potassium levels.
- Discuss current medications to avoid drug interactions.
- Assess blood pressure and fluid status.
- Understand potential risks like hyperkalemia.
Care During Medication
- Take medication exactly as prescribed.
- Regular monitoring of potassium and kidney function.
- Watch for symptoms like weakness or irregular heartbeat.
- Avoid potassium-rich supplements unless advised.
Care After Medication
- Continue routine follow-up and blood tests.
- Maintain low-salt, heart-healthy diet.
- Adjust dose under medical supervision if needed.
- Report side effects or worsening symptoms promptly.
Relevant Specialties

Cardiology
Our Cardiology Department delivers prevention, diagnosis and treatment for heart diseases through personalised care and advanced technology. Risk clinics for blood pressure and lipids offer non-invasive testing (ECG, echocardiogram, treadmill stress test, Holter monitor, and ambulatory blood pressure monitoring) and provide interventional services in a modern Catheterisation Laboratory, including device therapy and structural procedures. We maintain 24/7 cardiac ICU coverage and consultant availability to ensure rapid treatment for acute events. Post-procedure, patients receive tailored rehabilitation and multidisciplinary support that spans diabetes, pulmonary, and genetic services.




