PCSK9 Inhibitors
About the Procedure
PCSK9 Inhibitors are advanced lipid-lowering medications that significantly reduce LDL (‘bad’) cholesterol levels. They work by blocking the PCSK9 protein, allowing the liver to remove more LDL cholesterol from the blood. These injectable medications are especially useful for patients who cannot achieve target cholesterol levels with statins alone or who are statin-intolerant. PCSK9 Inhibitors lower the risk of heart attack and stroke and are used as part of long-term cardiovascular risk reduction strategies.
Care Before Medication
- Review lipid profile and cardiovascular risk status.
- Discuss prior response or intolerance to statins.
- Assess liver function and overall health.
- Learn injection technique and dosing schedule.
Care During Medication
- Administer injections as prescribed (usually every 2–4 weeks).
- Continue background lipid-lowering therapy if advised.
- Monitor cholesterol levels periodically.
- Watch for injection-site reactions or flu-like symptoms.
Care After Medication
- Maintain regular follow-up for lipid monitoring.
- Continue heart-healthy diet and lifestyle modifications.
- Adhere strictly to dosing schedule for optimal benefit.
- Report any side effects or concerns to healthcare provider.
Eligibility
- Patients with very high LDL cholesterol levels.
- Individuals with established cardiovascular disease.
- Patients with familial hypercholesterolemia.
- Those intolerant or inadequately controlled on statins.
Relevant Specialties

Cardiology
Our Cardiology Department delivers prevention, diagnosis and treatment for heart diseases through personalised care and advanced technology. Risk clinics for blood pressure and lipids offer non-invasive testing (ECG, echocardiogram, treadmill stress test, Holter monitor, and ambulatory blood pressure monitoring) and provide interventional services in a modern Catheterisation Laboratory, including device therapy and structural procedures. We maintain 24/7 cardiac ICU coverage and consultant availability to ensure rapid treatment for acute events. Post-procedure, patients receive tailored rehabilitation and multidisciplinary support that spans diabetes, pulmonary, and genetic services.




