Brain Tumors
About the disease & condition
Brain tumors are abnormal growths of cells within the brain or central nervous system (CNS). They can be primary (originating in the brain) or secondary (metastatic, spreading from cancer elsewhere in the body). Tumors are further classified based on cell type, location, and behavior (benign vs. malignant).
Known Symptoms
- General symptoms: Headaches (often worse in the morning or with Valsalva).
Nausea/vomiting, seizures, cognitive or personality changes.
Focal neurological deficits (e.g., weakness, sensory loss, vision changes, speech difficulties). - Red flag symptoms:
New-onset seizures in adults.
Progressive neurological deficits.
Signs of increased intracranial pressure (e.g., papilledema, lethargy).
Known Causes
- Primary tumors: Arise from brain cells (e.g., glial cells, meninges). Common types include gliomas (e.g., glioblastoma, astrocytoma), meningiomas, and pituitary adenomas.
- Metastatic tumors: Spread from cancers such as lung, breast, or melanoma.
Risk factors: Genetic syndromes (e.g., Neurofibromatosis, Li-Fraumeni), ionizing radiation exposure, family history (rare). - Pathophysiology: Tumor growth causes damage through mass effect (compression of brain tissue), increased intracranial pressure, infiltration of healthy tissue, and disruption of normal neural function.
Care
Prevention: No known primary prevention; avoid ionizing radiation when possible.
Follow-up: Regular MRI surveillance to monitor for recurrence or progression.
Rehabilitation (physical, occupational, speech therapy) as needed. Long-term management of treatment-related side effects.
Relevant Specialities
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