Constipation
About the disease & condition
Aetiology & Pathophysiology
- Primary (functional) causes: Slow transit constipation: Delayed colonic motility.
Defecatory disorders: Dysfunction of pelvic floor muscles or anal sphincter (e.g., dyssynergia). - Secondary causes: Diet: Low fiber intake, inadequate fluids. Medications: Opioids, anticholinergics, calcium channel blockers. Metabolic/endocrine: Hypothyroidism, diabetes, hypercalcemia. Neurological: Parkinson’s disease, spinal cord injury.
- Pathophysiology: Involves altered colonic motility, reduced stool water content, and/or impaired rectal evacuation.
Symptoms & Signs
Common symptoms: Straining during defecation. Lumpy or hard stools. Sensation of incomplete evacuation. Abdominal bloating or discomfort.
Red-flag symptoms: Unintended weight loss. Rectal bleeding or anemia. Acute onset in older adults. Family history of colorectal cancer or inflammatory bowel disease.
Diagnosis
Clinical assessment: Detailed history (bowel habits, diet, medications), physical exam (abdominal, digital rectal exam).
Diagnostic criteria: Rome IV criteria for functional constipation.
Additional testing (if indicated): Blood tests (thyroid function, calcium, glucose).
Colonoscopy (if red flags present). Anorectal manometry, balloon expulsion test (for defecatory disorders). Colonic transit study (e.g., radiopaque markers).
Management
- Non-pharmacological:
- Dietary modifications: Increased fiber and fluid intake.
Regular physical activity.
Bowel training (scheduled toilet visits).
- Dietary modifications: Increased fiber and fluid intake.
- Pharmacological:
- Fiber supplements (e.g., psyllium).
Osmotic laxatives (e.g., polyethylene glycol, lactulose).
Stimulant laxatives (e.g., bisacodyl, senna) for short-term use.
Prokinetic agents or secretagogues (e.g., lubiprostone, linaclotide) for chronic cases.
- Fiber supplements (e.g., psyllium).
- Biofeedback therapy:
- For dyssynergic defecation.
Potential Complications
- Fecal impaction: May lead to obstructive symptoms or overflow diarrhea.
- Hemorrhoids or anal fissures: Due to straining. Rectal prolapse.
- Reduced quality of life: Chronic abdominal pain, social distress.
Prevention & Follow-up
- Prevention: High-fiber diet, adequate hydration, and regular exercise. Avoidance of constipating medications when possible.
- Follow-up: Monitor response to dietary and lifestyle changes. Adjust laxative therapy as needed; avoid long-term stimulant use. Reevaluate if symptoms persist or worsen despite intervention.
Relevant Specialities

Gastroenterology
Gastroenterology is the specialty focused on the digestive system and its functions.
It supports patients with a wide range of digestive health concerns, helping maintain overall gastrointestinal health and well-being through early identification and long-term management.
At KIMSHEALTH, care is delivered through a patient-centered approach, focusing on accurate diagnosis, prevention, and ongoing support.

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It focuses on preventive care, early diagnosis, and the management of a wide range of health concerns, supporting long-term health and continuity of care.
At KIMSHEALTH, family medicine is delivered through a patient-first approach, emphasizing strong patient relationships, personalized care, and overall well-being.
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